PReS-FINAL-2233: Retrospective analysis of different treatment strategies in chronic non-bacterial osteomyelitis

نویسندگان

  • MM Kostik
  • IA Chikova
  • MF Dubko
  • LS Snegireva
  • VV Masalova
  • OV Kalashnikova
  • AY Mushkin
  • VG Chasnyk
چکیده

Introduction Pediatric chronic nonbacterial osteomyelitis (CNO) is a sterile inflammatory bone disorder in which innate and adaptive immunity dysfunction involved. Unifocal and multifocal disease courses are known. The modern treatment modalities include non-steroid anti-inflammatory drugs (NSAIDs), steroids, sulfasalazine (SSZ), methotrexate (MTX), bisphosphonates and biologic drugs TNFa and IL1b-antagonists, with limited data.

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عنوان ژورنال:

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2013